Research

Zhenyue ChenMore

  • Title:Professor
  • Tel:zhenyue_chen@tongji.edu.cn
  • Office:Ruian building room 701
  • Information of Tutors:Doctoral supervisor

Prof. Zhenyue Chen, Marie Skłodowska-Curie Fellow (EU Horizon 2020), doctoral supervisor and professor at the School of Physical Science and Engineering, Tongji University. He earned his Bachelor's degree in 2010 and Ph.D. in 2016 from Beijing Institute of Technology. Between 2016 and 2024, he conducted advanced research as a Postdoctoral Researcher and Research Scientist at globally renowned institutions including Technical University of Munich, Helmholtz Research Center (Germany), University of Zurich, and ETH Zurich (Switzerland). Specializing in innovative biomedical imaging technologies, Dr. Chen's research focuses on cutting-edge optoacoustic/photoacoustic imaging, optical imaging, and multimodal imaging system development. He has authored over 50 peer-reviewed publications in prestigious journals such as Light: Science & Applications, Nature Biomedical Engineering, Advanced Sciences and Nature Communications, with 15 of these as (co-)first or corresponding author.

  • Personal Experience
  • Research Areas
  • Teach Courses
  • Research Project
  • Academic Achievements
  • Honors and Awards

Work experience

September 2024 - present, Professor, Tongji University


Educational experience

August 2013 August 2015, College of Optical Sciences, University of Arizona, visiting PhD student

September 2010 - June 2016, School of Optics and Photonics, Beijing Institute of Technology, PhD degree in Optical Engineering

September 2006 - July 2010, School of Optics and Photonics, Beijing Institute of Technology, Bachelor’s degree in Electronic Science and Technology




Specializing in innovative biomedical imaging technologies, Dr. Chen's research focuses on cutting-edge optoacoustic/photoacoustic imaging, optical imaging, and multimodal imaging system development.


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Articles:

1. Z Chen, Q. Zhou, J. Droux, et al., Transcranial Cortex-Wide Imaging of Murine Ischemic Perfusion With Large-Field Multifocal Illumination Microscopy. Stroke 56(1), 170-182 (2025).

2. Q Zhou, C Glück, L Tang, et al. Z. Chen*, "Cortex-wide transcranial localization microscopy with fluorescently labeled red blood cells, " Nature Communications 15:3526 (2024). (Co-corresponding author)

3. I. Gezginer#, Z Chen#, H. Yoshihara, et al., Concurrent optoacoustic tomography and magnetic resonance imaging of resting-state functional connectivity in the mouse brain. Nature Communications 15, 10791 (2024). (#Contributed equally)

4. Z Chen, I Gezginer, Q Zhou, et al., "Multimodal optoacoustic imaging: methods and contrast materials," Chemical Society Reviews 53, 6068-6099 (2024).

5. Z Chen, I Gezginer, M Augath, et al., "Simultaneous Functional Magnetic Resonance and Optoacoustic Imaging of Brain‐Wide Sensory Responses in Mice, " Advanced Sciences 10 (3), 2205191(2023).

6. Z Chen, I Gezginer, M Augath, et al., "Hybrid magnetic resonance and optoacoustic tomography (MROT) for preclinical neuroimaging," Light: Science & Applications 11:332(2022).

7. Q Zhou#, Z Chen#, Y Liu, et al., "Volumetric wide-field fluorescence microscopy for cortical microcirculation mapping in murine brain, " Nature Communications 13 (1):7969 (2022). (#Contributed equally)

8. Z Chen, Q Zhou, XL Deán-Ben, et al., "Multimodal Noninvasive Functional Neurophotonic Imaging of Murine BrainWide Sensory Responses, " Advanced Sciences, 2105588 (2022).

9. R Ni#, Z Chen#, XL Deán-Ben#, et al., " Multiscale optical and optoacoustic imaging of amyloid-β deposits in mice," Nature Biomedical Engineering 6, 1031–1044 (2022). (#Contributed equally)

10. Z Chen, A Özbek, J Rebling, et al., "Multifocal structured illumination optoacoustic microscopy, " Light: Science & Applications 9 (1), 1-9 (2020).

11. Z Chen, B Mc Larney, J Rebling, et al., “HighSpeed LargeField Multifocal Illumination Fluorescence Microscopy,” Laser & Photonics Reviews 14 (2), 1900070 (2020).

12. Q Zhou, Z Chen, J Robin, et al., "Diffuse optical localization imaging for noninvasive deep brain microangiography in the NIR-II window," Optica 8, 796-803 (2021).

13. Z Chen, Q Zhou, J Rebling, D Razansky, “Cortexwide microcirculation mapping with ultrafast largefield multifocal illumination microscopy,” Journal of Biophotonics 13 (11), e202000198 (2020).

14. Z Chen, Q Zhou, J Robin et al., “Widefield fluorescence localization microscopy for transcranial imaging of cortical perfusion with capillary resolution,” Opt. Lett 45 (13), 3470-3473 (2020).

15. Z Chen, XL Deán-Ben, N Liu, et al., “Concurrent fluorescence and volumetric optoacoustic tomography of nanoagent perfusion and bio-distribution in solid tumors,” Biomed. Opt. Express 10 (10), 5093-5102 (2019).

16. Z Chen, XL Deán-Ben, S Gottschalk, et al., "Performance of optoacoustic and fluorescence imaging in detecting deep-seated fluorescent agents," Biomed. Opt. Express 9, 2229-2239 (2018).

17. Z Chen, L Dean-Ben, S, Gottschalk, et al., “Hybrid system for in vivo epifluorescence and 4D optoacoustic imaging”, Opt. Lett 42, 4577-4580 (2017).

18. Z Chen, X Wang, and R Liang, "Snapshot phase shift fringe projection 3D surface measurement," Opt. Express 23, 667-673 (2015).  

19. Z Chen, X Wang, and R Liang, "Calibration method of microgrid polarimeters with image interpolation," Appl. Opt. 54, 995-1001 (2015).

20. Z Chen, N Zhu, S Pacheco, et al., "Single camera imaging system for color and near-infrared fluorescence image guided surgery," Biomed. Opt. Express 5, 2791-2797 (2014).  

21. Z Chen, X Wang, and R Liang, "RGB-NIR multispectral camera," Opt. Express 22, 4985-4994 (2014).  

22. Z Chen, X Wang, S Pacheco, et al., "Impact of CCD camera SNR on polarimetric accuracy," Appl Optics 53, 7649-7656 (2014).




1. Marie Skłodowska-Curie Fellow (EU Horizon 2020)

2. Senior member of OPTICA

3. Senior member of SPIE